Edorium Journal of

Surgery

 
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Original Article
 
Glycemic changes after sleeve gastrectomy in type 2 diabetic morbidly obese patients
Tarek Osama Hegazy1, Ahmed Abd El-Halem Ewis2
1MD, MRCS, Lecturer in Department of General Surgery, Faculty of Medicine, Cairo University, Egypt.
2MSc Kasr El-Aini, Faculty of Medicine, Cairo University.

Article ID: 100001S05TH2014
doi:10.5348/S05-2014-1-OA-1

Address correspondence to:
Tarek Osama Hegazy
30, Anas Ben Malek st., el Mohandeseen
Giza
Egypt
Phone: 20 01222493066
Email: ticegy@yahoo.com

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How to cite this article:
Hegazy TO, Ewis AAE. Glycemic changes after sleeve gastrectomy in type 2 diabetic morbidly obese patients. Edorium J Surg 2014;1:1–8.


Abstract
Aims: Obesity is gradually turning into an epidemic condition throughout the world and has become a social psychological and economic burden of growing proportions. Bariatric surgery is known to be a highly effective and long lasting treatment for morbid obesity and many related conditions, including type 2 diabetes mellitus (T2DM) and the metabolic syndrome (MS). The aim of this study is to assess the short- and long-term effects of laparoscopic sleeve gastrectomy (LSG) on body weight and glucose homeostasis in morbidly obese diabetic patients.
Methods: That study was conducted on 40 patients, for the evaluation of the short- and long-term effects (one-day, three-month, six-month, nine-month and twelve-month) of LSG on body weight and glucose homeostasis by measuring fasting blood glucose level, postprandial blood glucose (PPBG), glycated hemoglobin (HbA1C), insulin level in morbid obese T2DM subjects not adequately controlled with medical therapy. Results: Resolution incidence by all parameters (FBG, PPBG and HbA1C) was 13 patient (32.5%), 27 patients (67.5%), 32 patients (80%) and 32 patients (80%) at third-month, sixth-month, ninth-month and 12th-month postoperatively, respectively.
Conclusion: In our study, the surgical procedure of laparoscopic sleeve gastrectomy resulted in marked weight loss and decrease in the body mass index which improved glucose homeostasis and remission of T2DM. Our study showed that the LSG is associated with a high rate of resolution of T2DM at 12-month after surgery in severely obese subjects with T2DM.

Keywords: Laparoscopic sleeve gastrectomy (LSG), Type 2 diabetes mellitus (T2DM), Morbid obese, Postprandial blood glucose (PPBG), Glycated hemoglobin (HbA1C), Insulin

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Author Contributions
Tarek Osama Hegazy – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Ahmed Abd El-Halem Ewis – Acquisition of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2014 Tarek Osama Hegazy et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.



About The Authors

Tarek Osama Hegazy is lecturer in Department of Surgery, Kasr al-Aini School of Medicine, Cairo University, Cairo, Egypt. He earned undergraduate degree (MBBCH) from Kasr al-Aini School of Medicine and postgraduate degrees (MSc) and (MD) from Department of Surgery Kasr al-Aini School of Medicine, Cairo University, Cairo, Egypt and (MRCS) from Royal College of Surgery, London, England. He has published six research papers in national and international academic journals.



Ahmed Abdel Halem Ewis (MBBCH, MSc) is Specialist of General Surgery, and a faculty in Department of Surgery, Faculty of Medicine, Cairo University, Egypt. His field of interest includes researching management of comorbidities of morbid obesity.




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